Exo-PDRN Prismatic+

NEW
Un frasco blanco con dispensador tipo pump del sérum Medik8 EXO-PDRN Prismatic+ Youthful Vitality Serum descansa sobre un fondo blanco, rodeado por una mancha transparente y brillante de la textura del sérum.
Primer plano de burbujas de líquido transparente sobre un fondo holográfico. Las líneas de texto destacan los ingredientes clave: Prismatic PDRN para ayudar a calmar el enrojecimiento visible y revelar una piel más suave y de aspecto más joven; Triple Exosome Complex con hasta 151 mil millones de exosomas por frasco para promover una tez de apariencia más saludable; GF MiniProtein™ para redefinir visiblemente la estructura de la piel con el tiempo; y ATP Precursor para optimizar los procesos naturales invol
Comparación del antes y después de la frente y el área de los ojos de una persona, con un círculo punteado que resalta una reducción visible de las arrugas en la frente. Debajo, un texto grande indica que el 100% de los participantes notó una reducción visible de las arrugas en 14 días.
Sérum Medik8 Exo-PDRN Prismatic+ presentado con el texto “Impulsa la rejuvenecimiento natural de la piel en más de un 50%*”, junto con beneficios que incluyen salud de la piel, volumen, luminosidad, tono de la piel, arrugas y firmeza.
Un gráfico que compara los niveles de penetración en la piel de diferentes tipos de PDRN mediante escaneos de mapas de calor. El título indica que el PDRN prismático representa una absorción cutánea 2 veces mayor que el PDRN tradicional, con una penetración un 60% más profunda. El mapa de calor de PDRN PRISMATIQUE muestra significativamente más áreas rojas y naranjas (alta detección) alcanzando capas más profundas de la piel en comparación con los escaneos de PDRN DE ROSE y PDRN DE SAUMON.
Un retrato de la Dra. Bibi Ghalaie, médica especialista en medicina estética, vistiendo una bata de laboratorio de Medik8, con el título "EMBAJADORA GLOBAL DE MEDIK8" y una cita que dice: "Hasta ese momento, no había encontrado un producto que realmente pudiera cerrar la brecha entre los tratamientos realizados en una clínica médica y el cuidado de la piel en casa; ¡este es ese producto! He visto resultados visibles en mis pacientes: la piel luce notablemente más flexible, tersa y rejuvenecida."
Exo-PDRN Prismatic+
Primer plano de una mujer sonriente tocando su mejilla, donde se aprecia una aplicación del sérum EXO PDRN de Medik8. Titulado "Resultados de Rejuvenecimiento Integral", con los siguientes beneficios: salud de la piel volumen luminosidad tono de la piel arrugas firmeza
Dos frascos de sérum Medik8 se encuentran uno al lado del otro sobre un fondo gris suave. El frasco blanco de EXO-PDRN Prismatic+ se describe como indicado para la rejuvenecimiento general y visible de la piel. El frasco negro de Liquid Peptides Advanced MP se describe como indicado para reducir visiblemente las arrugas profundas.
Comparación del antes y después del área externa de los ojos de una persona, con un círculo punteado que resalta una reducción visible de las patas de gallo. Debajo, un texto grande indica “7 días” para revelar una piel de aspecto más saludable, radiante y luminosa.
Comparación del antes y después del área debajo de los ojos y de las mejillas de una persona, con un círculo punteado que resalta la mejora en la textura de la piel. Debajo, el texto indica que está clínicamente comprobado que la piel se ve visiblemente más suave y tersa en un 43% en 7 días.
Una guía de aplicación para la rutina de día y de noche muestra productos Medik8 sobre un fondo gris claro con sutiles formas hexagonales. El frasco de EXO-PDRN Prismatic+ se destaca como el paso “CIBLE” (Objetivo) en ambas rutinas, utilizado después de la limpieza. Por la mañana, se continúa con Vitamina C y protector solar. Por la noche, se continúa con otro sérum objetivo (Liquid Peptides) y una crema hidratante.
Un frasco blanco con dispensador tipo pump del sérum Medik8 EXO-PDRN Prismatic+ Youthful Vitality Serum descansa sobre un fondo blanco, rodeado por una mancha transparente y brillante de la textura del sérum.
Primer plano de burbujas de líquido transparente sobre un fondo holográfico. Las líneas de texto destacan los ingredientes clave: Prismatic PDRN para ayudar a calmar el enrojecimiento visible y revelar una piel más suave y de aspecto más joven; Triple Exosome Complex con hasta 151 mil millones de exosomas por frasco para promover una tez de apariencia más saludable; GF MiniProtein™ para redefinir visiblemente la estructura de la piel con el tiempo; y ATP Precursor para optimizar los procesos naturales invol
Comparación del antes y después de la frente y el área de los ojos de una persona, con un círculo punteado que resalta una reducción visible de las arrugas en la frente. Debajo, un texto grande indica que el 100% de los participantes notó una reducción visible de las arrugas en 14 días.
Sérum Medik8 Exo-PDRN Prismatic+ presentado con el texto “Impulsa la rejuvenecimiento natural de la piel en más de un 50%*”, junto con beneficios que incluyen salud de la piel, volumen, luminosidad, tono de la piel, arrugas y firmeza.
Un gráfico que compara los niveles de penetración en la piel de diferentes tipos de PDRN mediante escaneos de mapas de calor. El título indica que el PDRN prismático representa una absorción cutánea 2 veces mayor que el PDRN tradicional, con una penetración un 60% más profunda. El mapa de calor de PDRN PRISMATIQUE muestra significativamente más áreas rojas y naranjas (alta detección) alcanzando capas más profundas de la piel en comparación con los escaneos de PDRN DE ROSE y PDRN DE SAUMON.
Un retrato de la Dra. Bibi Ghalaie, médica especialista en medicina estética, vistiendo una bata de laboratorio de Medik8, con el título "EMBAJADORA GLOBAL DE MEDIK8" y una cita que dice: "Hasta ese momento, no había encontrado un producto que realmente pudiera cerrar la brecha entre los tratamientos realizados en una clínica médica y el cuidado de la piel en casa; ¡este es ese producto! He visto resultados visibles en mis pacientes: la piel luce notablemente más flexible, tersa y rejuvenecida."
Exo-PDRN Prismatic+
Primer plano de una mujer sonriente tocando su mejilla, donde se aprecia una aplicación del sérum EXO PDRN de Medik8. Titulado "Resultados de Rejuvenecimiento Integral", con los siguientes beneficios: salud de la piel volumen luminosidad tono de la piel arrugas firmeza
Dos frascos de sérum Medik8 se encuentran uno al lado del otro sobre un fondo gris suave. El frasco blanco de EXO-PDRN Prismatic+ se describe como indicado para la rejuvenecimiento general y visible de la piel. El frasco negro de Liquid Peptides Advanced MP se describe como indicado para reducir visiblemente las arrugas profundas.
Comparación del antes y después del área externa de los ojos de una persona, con un círculo punteado que resalta una reducción visible de las patas de gallo. Debajo, un texto grande indica “7 días” para revelar una piel de aspecto más saludable, radiante y luminosa.
Comparación del antes y después del área debajo de los ojos y de las mejillas de una persona, con un círculo punteado que resalta la mejora en la textura de la piel. Debajo, el texto indica que está clínicamente comprobado que la piel se ve visiblemente más suave y tersa en un 43% en 7 días.
Una guía de aplicación para la rutina de día y de noche muestra productos Medik8 sobre un fondo gris claro con sutiles formas hexagonales. El frasco de EXO-PDRN Prismatic+ se destaca como el paso “CIBLE” (Objetivo) en ambas rutinas, utilizado después de la limpieza. Por la mañana, se continúa con Vitamina C y protector solar. Por la noche, se continúa con otro sérum objetivo (Liquid Peptides) y una crema hidratante.
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Exo-PDRN Prismatic+

  • Skin Health
  • |
  • Volume
  • |
  • Luminosity
Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex

Inspired by polynucleotide treatments, Exo-PDRN Prismatic+ has been expertly designed to deliver a multi-dimensional approach to visible skin health, boosting the skin’s natural rejuvenation by +50%*.

Powered by intelligent prismatic PDRN, with a stable tetrahedral structure that mimics an arrow’s aerodynamic form, to allow for optimal penetration. Prismatic PDRN delivers 2x better skin absorption and 60% deeper skin penetration than traditional PDRN**, to support skin recovery. The result? Rejuvenation for visibly enhanced luminosity and resilience.

A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting the skin’s natural signalling processes that facilitate skin resilience and reinforce the skin barrier.  An ATP Precursor supports the skin’s natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion. 

Powerful when used daily and ideal alongside professional treatments. Experience Exo-PDRN Prismatic+ Pro Concentrate, our professional-grade formula exclusive to clinics and the perfect pairing alongside microneedling. Find your clinic.

*Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours

**Proven via in vitro skin penetration study versus salmon and rose PDRN benchmarks

 
Full Size (30ml)

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Advanced Pro-Collagen+ Peptide Cream
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 Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster
Full Size (50ml)

Product Details

Key Benefits

Visible Skin Rejuvenation

Scientifically proven to boost the skin’s natural rejuvenation by over 50%.[1]

Refined Tone & Texture

Supports visibly smoother skin with improved tone and texture.

Optimal Skin Recovery Support

Designed to support the skin’s natural recovery processes, making it ideal for daily use and alongside professional treatments.

Restored Vitality & Luminosity

Clinically proven to improve the look of skin luminosity and vitality in 7 days.[2]

Visibly Calm, Resilient-Looking Skin

Clinically proven to improve skin barrier function in 7 days.[2]

Proven Results
Before
After
Before
After
+50% boost in natural skin rejuvenation[1]
7 days to improved skin barrier function[2]
7 days to improved skin luminosity[2]
7 days to visibly improved skin volume[2]
7 days to improved skin tone[2]
14 days to visibly improved wrinkles[2]
14 days to improved firmness[2]
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment[3]
98% agree the results continue to get better with time[3]
[1] Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours.

[2] Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week.
[3] Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study.
[4] Proven via in vitro skin penetration study versus salmon and rose PDRN benchmarks.

How to Use

First-time use

If you're new to Exo-PDRN Prismatic+ we recommend a patch test at least 24 hours before first use. Learn how to patch test here.

How To Use

After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.

Guide to Layering

Step 1: Cleanse

Tubo de Medik8 Surface Radiance Cleanse exhibido sobre un fondo blanco limpio con una gran mancha translúcida de textura en gel. El texto lo identifica como un gel limpiador renovador con AHA/BHA y mangostán, en un tamaño de 150 mL.
Morning
Evening
Surface Radiance Cleanse™
Full Size (150ml)

Step 2: Target

Un frasco blanco con dispensador tipo pump del sérum Medik8 EXO-PDRN Prismatic+ Youthful Vitality Serum descansa sobre un fondo blanco, rodeado por una mancha transparente y brillante de la textura del sérum.
Morning
Evening
Exo-PDRN Prismatic+
Full Size (30ml)

Step 3: Brighten

Botella de Medik8 C-Tetra Advanced mostrada sobre un fondo blanco limpio con gotas translúcidas de sérum, destacando su textura ligera de gel-sérum.
Morning
C-Tetra Advanced
Full Size (30ml)

Step 4: Renew

Medik8 Crystal Retinal Ceramide Eye 3: Tubo de crema junto a una muestra en zigzag de crema amarilla sobre un fondo blanco. Dos distintivos plateados destacan «GANADOR DE MÁS DE 4 PREMIOS GLOBALES» y «TECNOLOGÍA PATENTADA PRIMERA EN EL MUNDO».
Evening
Crystal Retinal® Ceramide Eye
Select a Size

Step 5: Moisturise

El envase de la crema «Medik8 Advanced Pro-Collagen+ Peptide Cream» abierto, en el que se aprecia una crema blanca y suave sobre un fondo blanco
Morning
Evening
Advanced Pro-Collagen+ Peptide Cream
Full Size (50ml)

Key Ingredients

Prismatic PDRN

A pioneering form of vegan (contains no animal derrived ingredients) PDRN with a stable tetrahedral structure for 100% better skin absorption than traditional PDRN.[4] Composed of DNA particles that penetrate 61% deeper than traditional PDRN[4] to support skin recovery, help soothe visible irritation and reveal smoother, more youthful-looking skin.

Triple Exosome Complex

Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.

GF MiniProteinTM

Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.

ATP Precursor

An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.

GF MiniProteinTM

Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.

ATP Precursor

An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.

Full List of Ingredients
Exo-PDRN Prismatic+
Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex

Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • Clinically proven
  • Fragrance-free
  • Dermatologically tested
  • Proven gentle formula
  • Certified by the vegan society

Experts Recommended

"Exo-PDRN Prismatic+ reflects our belief that visible rejuvenation comes from supporting the skin’s inherent biology. We engineered a formula that works with the natural processes skin relies on to recover and function at its best. By addressing Recover, Restore and Recharge together, we help create the optimal conditions for skin to look healthier and visibly rejuvenated."

Daniel Isaacs
Chief Product Officer & Founding Partner of Medik8

Complete Your Regime

Reviews

Frequently Asked Questions

Is it suitable for sensitive skin?

Yes. Exo-PDRN Prismatic+ is designed to be gentle and suitable for sensitive skin.

Can I use it with makeup?

Yes. Exo-PDRN Prismatic+ has been tested to layer seamlessly under makeup, making it ideal for everyday use.

Can I use it with sunscreen?

Absolutely. Its lightweight texture is designed to layer well under sunscreen, making it suitable for both morning and evening routines.

Can I use Exo-PDRN Prismatic+ with exfoliating acids?

Yes. Exo-PDRN Prismatic+ can be applied after exfoliating acids. We recommend following with a moisturiser to help support the skin barrier and minimise the risk of any dryness.

Can I use Exo-PDRN Prismatic+ with C-Tetra Advanced?

Absolutely. Exo-PDRN Prismatic+ and C-Tetra Advanced make an ideal duo to help improve the skin’s natural recovery mechanisms. Use C-Tetra Advanced to defend against premature skin ageing and achieve accelerated visible skin brightening, and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

Does the 'GF' in GF MiniProtein™ (found in Liquid Peptides Advanced MP, Advanced Pro-Collagen+ Peptide Cream, and Exo-PDRN Prismatic+) stand for Growth Factor?

Yes, the 'GF' on our packaging stands for Growth Factor MiniProtein™, a next-generation form of growth factor in skincare. Its small molecular size makes it more advanced than traditional options like TGF, EGF, and IGF, allowing it to unlock previously untapped cosmetic effectiveness within the skin's anti-ageing pathways.

Is Exo-PDRN Prismatic+ suitable for dry skin?

Yes. The formula contains hydrating and soothing ingredients, making it suitable for dry skin. Due to its water-light texture, we recommend following with a moisturiser for optimal comfort and results.

Is Exo-PDRN Prismatic+ suitable for oily skin?

Yes. Exo-PDRN Prismatic+ is oil-free and suitable for oily skin types. It delivers an instant healthy glow without leaving skin looking shiny.

Why are you not using spicules like other exosome serums on the market?

Spicules work by creating micro-channels through controlled micro-trauma. We chose not to include spicules as that can be unnecessarily harsh on post-treatment skin.

Instead, Exo-PDRN Prismatic+ uses a carefully engineered combination of advanced ingredients to deliver results in a gentler, more comfortable way, without placing unnecessary stress on the skin.

Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?

Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

Can I use Exo-PDRN Prismatic+ with Crystal Retinal?

Absolutely. Exo-PDRN Prismatic+ and Crystal Retinal make an ideal age-defying duo. Crystal Retinal is our iconic nightly vitamin A serum which targets all signs of skin ageing; wrinkles, firmness, elasticity, dark spots, skin texture, and more. Exo-PDRN Prismatic+ is a twice daily lightweight serum which supports long-term skin rejuvenation and recovery. We recommend layering thinnest to thickest, where Crystal Retinal would be applied after Exo-PDRN Prismatic+.

What does skin health mean to Medik8?

At Medik8, true skin health means supporting the skin’s inherent biology. It is about building a resilient skin barrier and providing the skin with support to help it function at its peak. When your skin is healthy, visible vitality and radiance naturally follows.Our Exo-PDRN Prismatic+ is the ultimate expression of this philosophy, utilising a 'Rejuvenation Blueprint' to recover, restore, and recharge the skin. Through our independent clinical trials 'overall skin quality and healthy appearance' were graded. While one end of the spectrum represented skin that looks dull, lax, or unhealthy, our ultimate goal is to guide the skin all the way to the gold standard on the other end of the spectrum. In our trials, this peak profile is officially defined as 'extremely healthy, vibrant, and radiant in appearance.' The result of our clinical trials using Exo-PDRN Prismatic+ was the the product was clinically proven to improve the appearance of skin health in 7 days.[2]

Is Exo-PDRN Prismatic+ suitable for oily skin?

Yes. Exo-PDRN Prismatic+ is oil-free and suitable for oily skin types. It delivers an instant healthy glow without leaving skin looking shiny.

Why are you not using spicules like other exosome serums on the market?

Spicules work by creating micro-channels through controlled micro-trauma. We chose not to include spicules as that can be unnecessarily harsh on post-treatment skin.

Instead, Exo-PDRN Prismatic+ uses a carefully engineered combination of advanced ingredients to deliver results in a gentler, more comfortable way, without placing unnecessary stress on the skin.

Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?

Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

Can I use Exo-PDRN Prismatic+ with C-Tetra Advanced?

Absolutely. Exo-PDRN Prismatic+ and C-Tetra Advanced make an ideal duo to help improve the skin’s natural recovery mechanisms. Use C-Tetra Advanced to defend against premature skin ageing and achieve accelerated visible skin brightening, and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

Does the 'GF' in GF MiniProtein™ (found in Liquid Peptides Advanced MP, Advanced Pro-Collagen+ Peptide Cream, and Exo-PDRN Prismatic+) stand for Growth Factor?

Yes, the 'GF' on our packaging stands for Growth Factor MiniProtein™, a next-generation form of growth factor in skincare. Its small molecular size makes it more advanced than traditional options like TGF, EGF, and IGF, allowing it to unlock previously untapped cosmetic effectiveness within the skin's anti-ageing pathways.

Can I use Exo-PDRN Prismatic+ with Crystal Retinal?

Absolutely. Exo-PDRN Prismatic+ and Crystal Retinal make an ideal age-defying duo. Crystal Retinal is our iconic nightly vitamin A serum which targets all signs of skin ageing; wrinkles, firmness, elasticity, dark spots, skin texture, and more. Exo-PDRN Prismatic+ is a twice daily lightweight serum which supports long-term skin rejuvenation and recovery. We recommend layering thinnest to thickest, where Crystal Retinal would be applied after Exo-PDRN Prismatic+.

What does skin health mean to Medik8?

At Medik8, true skin health means supporting the skin’s inherent biology. It is about building a resilient skin barrier and providing the skin with support to help it function at its peak. When your skin is healthy, visible vitality and radiance naturally follows.Our Exo-PDRN Prismatic+ is the ultimate expression of this philosophy, utilising a 'Rejuvenation Blueprint' to recover, restore, and recharge the skin. Through our independent clinical trials 'overall skin quality and healthy appearance' were graded. While one end of the spectrum represented skin that looks dull, lax, or unhealthy, our ultimate goal is to guide the skin all the way to the gold standard on the other end of the spectrum. In our trials, this peak profile is officially defined as 'extremely healthy, vibrant, and radiant in appearance.' The result of our clinical trials using Exo-PDRN Prismatic+ was the the product was clinically proven to improve the appearance of skin health in 7 days.[2]
Exo-PDRN Prismatic+
Full Size (30ml)
Full Size (30ml)