El envase de la crema «Medik8 Advanced Pro-Collagen+ Peptide Cream» abierto, en el que se aprecia una crema blanca y suave sobre un fondo blanco
Tarro de crema Medik8 Advanced Pro-Collagen+ Peptide mostrado sobre un fondo negro con gráficos estructurales abstractos. El texto afirma que ayuda a aumentar la producción de colágeno en un 45 % para una piel visiblemente más firme, una reducción de las arrugas y una mayor elasticidad.
7 días: Comparación de antes y después del área de los ojos de un participante durante 7 días, mostrada junto al tarro de crema Medik8 Advanced Pro-Collagen+ Peptide. El texto destaca que se ha demostrado que el producto reduce visiblemente la profundidad de las arrugas en 7 días.
28 días: Comparación de antes y después del rostro de un participante durante 28 días, mostrada junto al tarro de crema Medik8 Advanced Pro-Collagen+ Peptide. El texto destaca resultados clínicamente probados en suavidad, firmeza y textura.
Comparación de los tarros de Medik8 Advanced Night Restore y Advanced Pro-Collagen+ Peptide Cream mostrados uno al lado del otro sobre un fondo negro. El texto contrasta la fórmula nutritiva de noche (PM) de Night Restore con la nueva fórmula ligera Pro-Collagen+ para AM/PM, destacando su capacidad para aumentar la producción de colágeno y reducir las arrugas profundas.
Tarro de crema Medik8 Advanced Pro-Collagen+ Peptide mostrado con una cápsula de recarga reciclable flotando sobre él, sobre un fondo negro con gráficos hexagonales. El texto destaca un 94 % menos de embalaje y resultados visibles con menos residuos.
Primer plano del perfil del rostro de una modelo sobre un fondo negro con gráficos hexagonales. El texto indica que el 89 % estuvo de acuerdo en que no se han formado nuevas líneas desde que comenzaron a usar la crema.
Imagen cuadrada titulada «CÓMO APLICAR EN CAPAS», que muestra una rutina de cuidado de la piel de Medik8 paso a paso con iconos para uso AM y PM. La secuencia de AM incluye Limpieza, Vitamina C, Hidratación y Protector solar; la secuencia de PM incluye Limpieza, Tratamiento específico, Vitamina A e Hidratación. Medik8 Advanced Pro-Collagen+ Peptide Cream aparece destacada en el paso de «Hidratación» en ambas secuencias. El fondo es gris claro con sutiles gráficos hexagonales.
Crema «Medik8 Advanced Pro-Collagen+ Peptide Cream», mostrada con su caja blanca, la tapa plateada abierta y el frasco blanco sobre un fondo blanco impecable.
El envase de la crema «Medik8 Advanced Pro-Collagen+ Peptide Cream» abierto, en el que se aprecia una crema blanca y suave sobre un fondo blanco
Tarro de crema Medik8 Advanced Pro-Collagen+ Peptide mostrado sobre un fondo negro con gráficos estructurales abstractos. El texto afirma que ayuda a aumentar la producción de colágeno en un 45 % para una piel visiblemente más firme, una reducción de las arrugas y una mayor elasticidad.
7 días: Comparación de antes y después del área de los ojos de un participante durante 7 días, mostrada junto al tarro de crema Medik8 Advanced Pro-Collagen+ Peptide. El texto destaca que se ha demostrado que el producto reduce visiblemente la profundidad de las arrugas en 7 días.
28 días: Comparación de antes y después del rostro de un participante durante 28 días, mostrada junto al tarro de crema Medik8 Advanced Pro-Collagen+ Peptide. El texto destaca resultados clínicamente probados en suavidad, firmeza y textura.
Comparación de los tarros de Medik8 Advanced Night Restore y Advanced Pro-Collagen+ Peptide Cream mostrados uno al lado del otro sobre un fondo negro. El texto contrasta la fórmula nutritiva de noche (PM) de Night Restore con la nueva fórmula ligera Pro-Collagen+ para AM/PM, destacando su capacidad para aumentar la producción de colágeno y reducir las arrugas profundas.
Tarro de crema Medik8 Advanced Pro-Collagen+ Peptide mostrado con una cápsula de recarga reciclable flotando sobre él, sobre un fondo negro con gráficos hexagonales. El texto destaca un 94 % menos de embalaje y resultados visibles con menos residuos.
Primer plano del perfil del rostro de una modelo sobre un fondo negro con gráficos hexagonales. El texto indica que el 89 % estuvo de acuerdo en que no se han formado nuevas líneas desde que comenzaron a usar la crema.
Imagen cuadrada titulada «CÓMO APLICAR EN CAPAS», que muestra una rutina de cuidado de la piel de Medik8 paso a paso con iconos para uso AM y PM. La secuencia de AM incluye Limpieza, Vitamina C, Hidratación y Protector solar; la secuencia de PM incluye Limpieza, Tratamiento específico, Vitamina A e Hidratación. Medik8 Advanced Pro-Collagen+ Peptide Cream aparece destacada en el paso de «Hidratación» en ambas secuencias. El fondo es gris claro con sutiles gráficos hexagonales.
Crema «Medik8 Advanced Pro-Collagen+ Peptide Cream», mostrada con su caja blanca, la tapa plateada abierta y el frasco blanco sobre un fondo blanco impecable.
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Fine Lines & Wrinkles

Advanced Pro-Collagen+ Peptide Cream

  • Firm
  • |
  • Hydrate
  • |
  • Renew
Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster

Help increase collagen production by 45%[1] and promote optimal skin longevity with Advanced Pro-Collagen+ Peptide Cream. Expertly formulated with advanced actives that help stimulate the skin’s natural collagen production to support visible firmness, elasticity and reduce deep-set wrinkles. It delivers fast-acting, clinically proven results in just 7 days while helping to prevent the appearance of future signs of skin ageing.[2]

Powered by regenerative science, this high-performance formula blends next-generation Growth Factor MiniProteinTM, NAD+ Longevity Booster, and Anti-A.G.E. Peptide to help visibly restore your skin’s structure for a visibly youthful, lifted and sculpted appearance. Powerful when used alone or post-treatment.

(50ml)
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El tubo de Medik8 Crystal Retinal 3 descansa sobre una franja de sérum rosa pálido sobre un fondo blanco. Distintivos destacan «Ganador de los Get The Gloss Beauty Awards 2025» y «Primera tecnología patentada del mundo», junto con el texto: «El sérum facial dermatológico n.º 1 del Reino Unido*».
Crystal Retinal®
  • Renew
  • |
  • Firm
  • |
  • Smooth
 Award-winning Age-Defying Vitamin A Night Serum
Select a Size
Key Benefits
Increased Skin Longevity

Engineered to support collagen production, the foundation of firm, resilient skin for visible strength that lasts.

Deep-Set Wrinkle Reduction

Clinically proven to visibly improve the look of wrinkles in just 1 use and reduce wrinkle depth in 7 days.[2]

Combat Skin Laxity

Clinically proven to visibly improve skin firmness in 7 days for skin more supple and youthful-looking.[2]

Lift Facial Contours

Clinically proven to visibly lift the skin and improve elasticity in 7 days to help maintain long-term skin quality.[2]

Proven Results
45% increase in collagen production[1]
7 days to visibly improve firmness and the look of skin fatigue[2]
7 days to visibly lift skin and reduce wrinkle depth[2]
7 days to visibly increase elasticity[2]
35% increased hydration after 1 use[2]
89% agree no new lines have formed since using the cream[3]
[1] Proven via ex vivo collagen study using Advanced Pro-Collagen+ Peptide Cream
[2] Proven via independent clinical study on Advanced Pro-Collagen+ Peptide Cream on 60 volunteers over 1 week

[3] Proven via independent consumer study on Advanced Pro-Collagen+ Peptide Cream on 113 volunteers over 4 weeks
How to Use

First-time use

If you’re new to Advanced Pro Collagen+ Peptide Cream, we advise performing a patch test at least 24 hours before first use. Learn how to patch test here.

Step 1

After cleansing in the morning and evening, apply Advanced Pro-Collagen+ Peptide Cream evenly across the face, neck & décolletage. Use light upward strokes and allow the cream to fully absorb.

Step 2

After morning application, apply sunscreen. We recommend Advanced Day Ultimate Protect.

Step 3

Refill pot (Sold separately)

To remove the empty inner pot from the reusable glass jar, press firmly above the 'P' to release it, then place it in your sorting bin (check locally). Align the lip of your new refill pot with the indent opposite the 'P' and press down until it clicks. Peel off the top seal and place it in your local sorting bin (check locally).

Note: The outer glass jar, inner pot, and lid are recyclable, if placed in the sorting bin (check locally). The inner pot and lid contain 30% post-consumer recycled content, excluding dyes and additives.

Available Strengths

OUR AGE-DEFYING MOISTURISERS

Choose Advanced Pro-Collagen+ Peptide Cream if your goal is to boost collagen production and support overall skin longevity. It’s expertly formulated to target deeper signs of skin ageing.

Choose Advanced Night Restore if your focus is on reducing stubborn wrinkles, especially when using actives like vitamin A. It calms, nourishes and strengthens skin while you sleep.

Key Ingredients
Growth Factor MiniProtein™

Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.

NAD+ Longevity Booster

Supports skin longevity to delay visible skin ageing, preserving the skin’s structure and long-term quality.

Anti-A.G.E. Peptide (Carnosine)

Helps the prevention of new lines and wrinkles by blocking skin-damaging sugars from binding to collagen in the skin in a process called glycation.

Encapsulated Endonuclease (pronounced ‘endo-new-cle-aise’)

Helps to protect from the visible effects of sun damage and promotes skin recovery after exposure.

Anti-A.G.E. Peptide (Carnosine)

Helps the prevention of new lines and wrinkles by blocking skin-damaging sugars from binding to collagen in the skin in a process called glycation.

Encapsulated Endonuclease (pronounced ‘endo-new-cle-aise’)

Helps to protect from the visible effects of sun damage and promotes skin recovery after exposure.

Polyglutamic Acid

Works in harmony with hyaluronic acid to deeply nourish, plump and lock in moisture.

Full List of Ingredients
Advanced Pro-Collagen+ Peptide Cream
Rejuvenating Anti-Wrinkle Moisturiser With GF MiniProteinTM & NAD+ Longevity Booster

Aqua (Water), Squalane, Caprylic/Capric Triglyceride, Lavandula Angustifolia (Lavender) Flower Water, Glycerin, Dimethicone, Stearic Acid, Phytosteryl Oleate, C12-16 Alcohols, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Maltodextrin, Carnosine, Rosmarinus Officinalis (Rosemary) Water, Cetearyl Alcohol, Butyrospermum Parkii (Shea) Butter, Ceramide NP, Linoleic Acid, Cetearyl Olivate, Palmitic Acid, Behenyl Alcohol, Tocopheryl Acetate, Collagen Amino Acids, Micrococcus Lysate, Hydrogenated Lecithin, Oligopeptide-1, Sorbitan Olivate, Helianthus Annuus (Sunflower) Sprout Extract, Xanthan Gum, Citric Acid Monohydrate, Sodium Hyaluronate, Ethylhexylglycerin, Sodium Gluconate, Sodium Polyglutamate, Acetyl Glucosamine, Hydroxyacetophenone, Phytosterols, Sodium Lauroyl Lactylate, Lecithin, Cholesterol, Ceteareth-25, Ceramide AP, Phytosphingosine, Carbomer, Cetyl Alcohol, Behenic Acid, Ceramide NS, Ceramide EOP, Ceramide EOS, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Phenoxyethanol, Ascorbyl Palmitate, Tocopherol, Glyceryl Stearate, Glyceryl Oleate, Citric Acid.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • Clinically proven
  • Non-comedogenic
  • Artificial fragrance-free
  • Dermatologically tested
  • Proven gentle formula
  • Certified by the vegan society
Experts Recommended

We engineered this formula for multi-faceted support to help enhance and preserve collagen reserves, promoting an environment where collagen in the skin thrives; for a naturally rejuvenated and healthy looking complexion with less visible lines & wrinkles.

DANIEL ISAACS
Chief Product Officer & Founding Partner Of Medik8

Find Your Moisturiser

El tarro de cristal de Medik8 Daily Radiance Vitamin C aparece abierto con una generosa punta de crema amarillo pálido en la parte superior. El texto identifica el producto como una crema hidratante dos en uno C-Tetra Cream SPF 30 de 50 mL.
Morning
Daily Radiance Vitamin C™
| €80
Benefits
  • 7% Tetrahexyldecyl Ascorbate
  • Advanced UV Filters
  • Hyaluronic Acid
  • Vitamin E
Concern
  • Instant brightening
  • Sun protection
  • Hydration
Key Ingredients

All Skin Types

Skin Types

Dullness

Tarro esmerilado de tamaño viaje de 12,5 ml de Medik8 Total Moisture Daily Facial Cream colocado junto a su caja de cartón blanca a juego. Los productos se muestran sobre una superficie gris texturizada, con un fondo blanco limpio. El texto en ambos indica: «Hidratación multicapa AM/PM con H.E.O.™ y péptidos prebióticos».
Morning
Evening
Total Moisture Daily Facial Cream™
| €60
Benefits
  • Prebiotic Peptide
  • Multi-Weight Hyaluronic Acid
  • Ceramides & Lipids
Concern
  • Deep & Lasting Moisturisation - Day or Night
  • Instantly Plump, Supple Skin
  • Clinically Proven Skin Barrier Support
  • Healthier Skin in 1 Hour
  • Perfect Base For Makeup
Key Ingredients

Dry & dehydrated skin

Skin Types

All skin types, great for sensitive

El tarro de crema Advanced Night Restore aparece abierto con una generosa porción de crema blanca en la parte superior, sobre un fondo blanco limpio, destacando su textura suave y reparadora. El texto negro del envase lo describe como “Crema de noche rejuvenecedora con multiceramidas”.
Evening
Advanced Night Restore™
| €76
Benefits
  • Multi-Ceramide Complex (with essential lipids)
  • Midnight Antioxidant Complex
  • Saskatoon Berry
  • ​​Dragon Fruit Extract
  • ​​N-Acetyl Glucosamine (NAG)
Concern
  • Nourishing
  • Firming
Key Ingredients

Fine lines & wrinkles

Skin Types

All Skin Types

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|
Benefits
  • Rejuvenating
  • Anti-wrinkle
Concern
  • Growth Factor MiniProtein™
  • NAD+ Longevity Booster
  • Anti-A.G.E. Peptide (Carnosine)
  • Encapsulated Endonuclease (pronounced ‘endo-new-cle-aise’)
  • Polyglutamic Acid
Key Ingredients

All Skin Types

Skin Types

Visible deep-set signs of ageing

Complete Your Regime

Reviews

Frequently Asked Questions

What does Skin Longevity mean at Medik8?
At Medik8, skin longevity means supporting your skin to look and feel its best, not just today but for years to come. It’s our science-first approach to maintaining long-term skin quality by targeting key markers of youthful-looking, more resilient skin. Advanced Pro-Collagen+ Peptide Cream is precisely formulated with advanced actives that help stimulate the skin’s natural collagen production to support the essential building blocks of skin longevity and promote visible firmness, elasticity and reduce deep-set wrinkles.
Should I use Advanced Pro-Collagen+ Peptide Cream in the morning or at night?
Both! This collagen-supporting moisturiser is formulated for day and night use, delivering visible benefits around the clock. In the morning, it layers beautifully under SPF and makeup. At night, it works alongside your actives to deeply hydrate and help restore a visible bounce-back effect, skin resilience and firmness while you sleep.
How do I layer Advanced Pro-Collagen+ Peptide Cream in my routine?
Advanced Pro-Collagen+ Peptide Cream is your moisturising step and is designed to slot effortlessly into both your morning and evening skincare routines. In the morning, apply after your targeted serums, such as Liquid Peptides Advanced MP and C-Tetra Advanced, and then follow with sunscreen. In the evening, use after your favourite actives and vitamin A serum. Apply as your final step to lock in hydration and support overnight skin renewal.
Does Advanced Pro-Collagen+ Peptide Cream contain fragrance or essential oils?
Advanced Pro-Collagen+ Peptide Cream does not contain any artificial fragrance or essential oils. It contains a mix of floral and herbal waters that lend a subtle aroma to the overall fragrance.
Is Advanced Pro-Collagen+ Peptide Cream suitable for use during pregnancy or nursing?

Unfortunately, as a cosmetic brand, we are unable to provide specific medical advice relating to our products. We would strongly advise speaking with your GP or midwife so that they can give you an accurate recommendation. The full ingredients list for each of our products can be found on the product pages of the Medik8 website.

As general guidance, Advanced Pro-Collagen+ Peptide Cream does not contain any ingredients which we would recommend avoiding during pregnancy unless advised by your doctor.  For clinically proven visible wrinkle reduction, it’s a great choice while avoiding retinoids or high-strength exfoliating acids that are not recommended during pregnancy.

Is Advanced Pro-Collagen+ Peptide Cream suitable for sensitive skin?
Yes, Advanced Pro-Collagen+ Peptide Cream is formulated for sensitive skin.
Can I use Advanced Pro-Collagen+ Peptide Cream with Liquid Peptides Advanced MP?
Absolutely. Liquid Peptides Advanced MP and Advanced Pro-Collagen+ Peptide Cream make an ideal collagen-boosting duo. Use Liquid Peptides Advanced MP to instantly target expression lines and build visible deep-set wrinkle reduction over time. Reach for Advanced Pro-Collagen+ Peptide Cream to trigger the foundations of skin longevity to achieve visibly stronger, smoother and revitalised skin.
Can I use Advanced Pro-Collagen+ Peptide Cream with Crystal Retinal?
Absolutely. Advanced Pro-Collagen+ Peptide Cream and Crystal Retinal make an ideal age-defying duo. Crystal Retinal is our iconic retinoid serum which targets all signs of skin ageing; wrinkles, firmness, elasticity, dark spots and skin texture (& more).  Follow with Advanced Pro-Collagen+ Peptide Cream to trigger the foundations of skin longevity with results starting in just 7 days.[1]
Is Advanced Pro-Collagen+ Peptide Cream suitable for sensitive skin?
Yes, Advanced Pro-Collagen+ Peptide Cream is formulated for sensitive skin.
Can I use Advanced Pro-Collagen+ Peptide Cream with Liquid Peptides Advanced MP?
Absolutely. Liquid Peptides Advanced MP and Advanced Pro-Collagen+ Peptide Cream make an ideal collagen-boosting duo. Use Liquid Peptides Advanced MP to instantly target expression lines and build visible deep-set wrinkle reduction over time. Reach for Advanced Pro-Collagen+ Peptide Cream to trigger the foundations of skin longevity to achieve visibly stronger, smoother and revitalised skin.
Can I use Advanced Pro-Collagen+ Peptide Cream with Crystal Retinal?
Absolutely. Advanced Pro-Collagen+ Peptide Cream and Crystal Retinal make an ideal age-defying duo. Crystal Retinal is our iconic retinoid serum which targets all signs of skin ageing; wrinkles, firmness, elasticity, dark spots and skin texture (& more).  Follow with Advanced Pro-Collagen+ Peptide Cream to trigger the foundations of skin longevity with results starting in just 7 days.[1]
Advanced Pro-Collagen+ Peptide Cream
(50ml)
(50ml)